Your Guide to Genetics & Nutrition
Representing over 500 hours of research, the Gene Food Guide to Nutrigenomics was built to catalogue genetic markers that can be influenced by nutrition. Before building the personalized nutrition algorithm we now offer to consumers and health systems, our research team, led by geneticist Dr. Aaron Gardner compiled an exhaustive list of the scientific research in the field of nutrigenomics. Applicable genes were scored based on the state of the scientific evidence with a Science Grade and published, with citations, in the guide. Genes that had sufficient evidence were included in our algorithm and weighted based on strength of research. The guide is updated regularly as new research emerges.
Genes
90+
SNPs
170+
Citations
500+
| Gene | Normal Function | SNP ID | Major Allele | Minor Allele | |
|---|---|---|---|---|---|
| IL6 | IL-6 is a signaling molecule which transmits signals between cells, especially those of the immune system. | C-237G, C-174G | g | c | |
| IL8 | IL-8 is a signalling molecule, used to transmit messages between cells and tissues in the body. | A-352T | a | t | |
| KIAA1109 | This protein produced by this gene is believed to play a role in guiding the growth and differentiation of epithelial cells and also in the onset of tumors. | a | g | ||
| KL | A protein with diverse functions shown to possess anti-aging and neuroprotective properties. | T33054001G | t | g | |
| G33054056C | g | c | |||
| LDLR | LDLR is a receptor protein which specifically recognises LDL particles. | G67+2015T | g | t | |
| LPA |
LPA is one of the major lipoproteins found in our body, responsible for cholesterol transport. |
19986711A>G | t | c | |
| 82290T>C | a | g | |||
| Ile1891Met | t | c | |||
| LPL |
LPL is an enzyme which regulates triglycerides in lipoproteins, and their uptake by cells. Situated on the surface of capillary cells, this enzyme plays a crucial role in the breakdown and assimilation of dietary fat. |
19986711A>G | a | g | |
| MADD | MADD is thought to regulate controlled cell death but is also implicated in other cellular events. | 47336320A>T | a | t | |
| MAOA | MAOA is an enzyme involved in the processing of neurotransmitters, it is sometimes called the "warrior" gene due to proposed links with aggression. | T1410C | c | t | |
| G1052+680C | g | c | |||
| G891T | t | g | |||
| C306+527T | t | c | |||
| MAOB | MAOB is an enzyme involved in the processing of neurotransmitters, it's importance relative to MAOA is under debate. | A1348-36G | a | g | |
| MAT1A | MAT1A is an enzyme responsible for the formation of SAM, a methyl donor molecule key in many other biological processes. | G791A | g | a | |
| MLXIPL | A transcription factor that regulates glycolysis (an cycle of biochemical reactions generating energy from glucose) and lipid production, predominantly in the liver | T73020301C | c | t | |
| MTHFD1 | MTHFD1 is an enzyme is an enzyme involved in the conversion of dietary folate into a variety of key products. | G1958A | g | a | |
| MTHFR | MTHFR is an involved in the conversion of dietary folate into a variety of key products. | C667T | c | t | |
| C117T | c | t | |||
| A1298C | a | c | |||
| MTNR1B | MTNR1B is a receptor for melatonin, one of the key sleep hormones. | C2120T | c | t | |
| MTR |
MTR is responsible for the regeneration of methionine from homocysteine. |
2756A>G | a | g | |
| MTRR | MTRR is an enzyme which helps maintain methionine synthase function, a key component of the methionine cycle. | A66G | a | g | |
| MUC1 | Muc1 protein forms part of the protective mucus layer which lines our lungs and digestive system. | C/G66A | a | g | |
| NAF1 | NAF1 is a key component of the telomerase enzyme. | n/a | g | a | |
| NOD2 | NOD2 plays an important role in the immune system. | C2104T | c | t | |
| G30491C/T | g | c |