Your Guide to Genetics & Nutrition
Representing over 500 hours of research, the Gene Food Guide to Nutrigenomics was built to catalogue genetic markers that can be influenced by nutrition. Before building the personalized nutrition algorithm we now offer to consumers and health systems, our research team, led by geneticist Dr. Aaron Gardner compiled an exhaustive list of the scientific research in the field of nutrigenomics. Applicable genes were scored based on the state of the scientific evidence with a Science Grade and published, with citations, in the guide. Genes that had sufficient evidence were included in our algorithm and weighted based on strength of research. The guide is updated regularly as new research emerges.
Genes
90+
SNPs
170+
Citations
500+
| Gene | Normal Function | SNP ID | Major Allele | Minor Allele | |
|---|---|---|---|---|---|
| FADS2 | FADS2 is a key enzyme in polyunsaturated fatty acid biosynthesis. | A61830500G | a | g | |
| FGFR1 | A receptor for growth factors involved in the control of cell division, differentiation and metabolism | T38474800C | t | c | |
| FGFR2 | FGFR2 is a receptor protein which binds fibroblast growth factor, which typically promotes cell division and differentiation. | rs1219515 | g | a | |
| FTO | FTO is an enzyme which has been linked with an increased risk of obesity. | G76373A | g | a | |
| G67694A | g | a | |||
| T77812C | t | c | |||
| G67880A | g | a | |||
| C83401A | c | a | |||
| T87653A | t | a | |||
| FUT2 | FUT2 is a protein which plays an important role in the creation in A or B antigens in A/B/O antigen types. | G12447A | g | a | |
| G6PD | G6PD is an enzyme which produces NADPH, key in the biosysnthesis of many molecules and in oxidative defense. | A466G | a | g | |
| G292A | g | a | |||
| GAD1 | GAD1 is an enzyme which catalyzes the formation of the important neurotransmitter GABA. | G638+315C | g | c | |
| C170814316A | c | a | |||
| GC | GC is a protein which binds to vitamin D allowing for its efficient transport around the body. | A26-796C | t | c | |
| GCKR |
GCKR is a protein produced in the liver which regulates glucose metabolism. |
26532T>C | c | a | |
| GCLC | GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione. | C53410037T | c | t | |
| GCLM | GCLC forms part of glutamate-cysteine ligase which forms part of the pathway that produces the vital antioxidant glutathione. | C-590T | c | t | |
| GJB2 |
Connexin 26 is involved in the transport of potassium ions and other small molecules between adjacent cells. |
A20216312G | a | g | |
| GPX1 | GPX1 is a peroxidase enzyme which plays a key antioxidant role. | C599T | c | t | |
| GPX4 | GPX4 is a peroxidase enzyme which plays a key antioxidant role. | T660C | c | t | |
| GRIA3 | GRIA3 is a glutamate receptor important in neuronal signaling. | A17114C | a | c | |
| G11395A | g | a | |||
| GSTP1 | GSTP1 is an enzyme which assists the antioxidant glutathione remove harmful reactive oxygen species. | A313G | a | g | |
| HMGCR | An enzyme in the biochemical pathway that produces cholesterol. | T75360714C | t | c | |
| HNMT | HNMT breaks down the molecule histamine which is important in the immune response. | C314T | c | t | |
| IL10 | IL-10 is an anti-inflammatory cytokine which acts to damp down the immune systems inflammatory response. | A-1117G | a | g | |
| IL23R | IL23R is the receptor for the protein IL-23, which is involved in the immune response. | G533A | g | a |