Heart Health Genes - Page 3 Dr. Gina Leisching Heart Health Genes F8 F8 is an essential blood clotting protein. Gastrointestinal Genes CBS CBS is an enzyme which converts homocysteine into cystathionine, the first step of the transsulfuration pathway. Heart Health Genes ACYP2 ACYP2 is an enzyme which controls the movement of ions across the cell membrane, specifically muscle cells. Heart Health Genes ACE ACE is an enzyme which converts the inactive protein angiotensin I into the active angiotensin II, which is key in regulating blood pressure. Gastrointestinal Genes ABCG8 ABCG8 is a transporter protein, controlling the absorption and excretion of cholesterol and other lipids in the gut. Heart Health Genes SHMT1 SHMT1 is an enzyme of the one carbon cycle, converting folate into a variety of other cellular products. Heart Health Genes MTHFR MTHFR is an involved in the conversion of dietary folate into a variety of key products. « 1 2 3