Heart Health Genes - Page 2 Dr. Gina Leisching Heart Health Genes DHCR7 The DHCR7 gene encodes the enzyme 7-dehydrocholesterol reductase, which is essential for the production of cholesterol. Heart Health Genes APOA2 APOA2 is the second most abundant protein found in high-density lipoprotein particles. Heart Health Genes PPARG PPARG is a receptor protein mainly expressed in adipose tissue that regulates glucose metabolsim. Heart Health Genes LDLR LDLR is a receptor protein which specifically recognises LDL particles. Heart Health Genes FADS1 FADS1 is an enzyme which desaturates fatty acids by introducing double bonds, an important step in the metabolism of polyunsaturated fats. Heart Health Genes CETP CETP is an enzyme involved in the metabolism of lipoproteins. Heart Health Genes CELSR2 CELSR2 is a protein important in cell to cell communication. Heart Health Genes APOB APOB is the main apolipoprotein found in low density lipoproteins, important for carrying dietary lipids through the blood. Heart Health Genes AHCY AHCY is an enzyme which breaks down adenosylhomocysteine into adenosine and L-homocysteine, which are required for several cellular processes. Heart Health Genes CPS1 CPS1 is a mitochondrial enzyme involved in the metabolism of proteins and ammonia. Heart Health Genes APOE APOE is an apolipoprotein with a major role in transporting cholesterol in the brain. Heart Health Genes NOS3 NOS3 is an enzyme responsible for synthesizing nitric oxide, which is important in many biological processes, especially cardiac function. « 1 2 3 »